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Agree to disagree image nostr:nevent1qvzqqqqqqypzple0fntcdeptgv3hf8y329lv0whj9h7sxkm6zqd74qaku27t4ng4qqst7e3wa5m4qzxsqyhp978zd4j33flq4glp5ujxn7wn7f4erxdvd6c4sph8x
2025-06-05 10:21:09 from 1 relay(s) View Thread →
Increasing SPARCL-1 in the hippocampus shown to reverse cognitive decline in a mouse model of Alzheimer's as well as in general age related cognitive decline of other mice. No effect on amyloid plaque, putting another nail in the coffin of that research. https://doi.org/10.1111/acel.14493 Increased SPARCL-1 is also seen in MS and neuropathic pain so this probably can't be a preventative therapy.
2025-06-04 07:13:44 from 1 relay(s) View Thread →
https://archive.is/xVJt1 nostr:nevent1qvzqqqqqqypzqkqnevxq3w25wevhdl5cvl4r3v432f8rnv0ht2ezkvnwykpn4fmxqyt8wumn8ghj7un9d3shjtnddaehgu3wwp6kytcpz4mhxue69uhhyetvv9ujuerpd46hxtnfduhsqgzh7tjzmr3y2pclnacs6g5xehjaxsmtg08mhze3tclayfhtsu93lg86dl5c
2025-06-03 13:10:25 from 1 relay(s) View Thread →