Interesting cyborg-modification reported in Cell: https://www.cell.com/cell/fulltext/S0092-8674(25)00454-4 "Near-infrared spatiotemporal color vision in humans enabled by upconversion contact lenses" #science #cyborg

Giveaway 1,000 sats for the next 20 reposts, 500 for the next 15! I'm doing a Zapvertising experiment to promote my bitcoin novel „Walking Banks“ /

Walking Banks - A Novel

on Nostr and test if one can broaden an audience this way . In addition to the Zapvertisment Zaps you can unlock 800000 sats: If your up for a treasure hunt, the book contains a real Bitcoin seed phrase hidden within the story. So if you can piece the right string of words together, it leads to a wallet with 800000 sats in it. No funny business, all real. The first one to figure it out gets the bitcoin. The book is out as on audiobook, e-book and print on Amazon (https://www.amazon.com/Walking-Banks-Mystery-Novel-White/dp/B0DCNZLV6H) so go and check it out. Also, if you're using Nostr you can listen to the audiobook for free on Fountain (fountain.fm/album/JYWZOPSrol8fvWpjNt8q) or search for „Walking Banks“ in the music section. Otherwise the audiobook is also available now on Spotify, Apple Books, Google play, Kobo, and pretty much everywhere else too. #bitcoin #books #novel #story #art #zapvertising #nostr

Is ChatGTP just a human with a brain disorder? "Comparison of Large Language Model with Aphasia" paper outlining that there is "a surprising similarity between the way large language models (LLMs) like ChatGPT process information and how the brains of people with Wernicke’s aphasia function. In both cases, fluent but often incoherent output is produced, suggesting rigid internal processing patterns that can distort meaning."

Neuroscience News

AI Chatbots Mirror a Human Brain Disorder - Neuroscience News

Researchers have found a surprising similarity between the way large language models (LLMs) like ChatGPT process information and how the brains of ...

https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202414016 #llm #ai #chatgtp #science #brain

I'm really excited to share that my Bitcoin Novel „Walking Banks“ is now out as an audiobook! It’s been a wild ride getting this story out into the world, and hearing it come alive through the voice of Adrian Lopez, @adrianmlopez (who absolutely nailed the narration) has been surreal. If you're using Nostr (and since you are reading this you are), you can listen to the audiobook for free on Fountain (fountain.fm/album/JYWZOPSrol8fvWpjNt8q) or search for „Walking Banks“ in the music section. Otherwise the audiobook is also available now on Spotify, Apple Books, Google play, Kobo, and pretty much everywhere else too... I just cannot get it placed on audible yet but am working on it. Also…I hid something inside the book: The information for a real Bitcoin seed phrase can be found across the story that leads to a wallet with 0.008 BTC in it. Yep, it’s real. The first one to figure it out gets the treasure. More info is up at walkingbanks.com. I would love for you to check it ouvand if you do, let me know what you think. #bitcoin #books #novel #story #art

Fianlly some progress in ALS research, the disease that took Hal Finney's life. A new ALS clinical phase 2b study shows promising data: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00262-4/fulltext It doesn't look like much but if this survival data holds up in a phase 3, this would be the first new treatment option for ALS patients that can meaningfully slow down their disease progression (look at figure 2 c,d). Fingers crossed!

#bitcoin

It was dark, the moon shone bright, the green meadow was covered in snow, when a carriage sped by lightning-fast, slowly turning the corner. Inside, people were standing seated, deep in silent conversation, when a shot rabbit went ice-skating on the sandy bank. And a blond-haired young man with coal-black hair sat on a green box, which was painted red. Next to him, an old spinster, barely sixteen years old, held a butter roll in her hand, which was smeared with lard. #poetry

Good Morning and Merry Christmas ! #nostr

Another unfortunate clinical trial failure for a CNS indication (Parkinson). All primary and secondary endpoints were missed:

Findings from minzasolmin proof-of-concept ORCHESTRA study shape next steps in UCB Parkinson’s research program | UCB

Findings from minzasolmin proof-of-concept ORCHESTRA study shape next steps in UCB Parkinson’s research program | UCB

#science #parkinson #neurodegeneration #brain

This is really interesting: https://www.nature.com/articles/s41562-024-02046-9 "Large language models surpass human experts in predicting neuroscience results" A study on how well trained LLMs can predict the "correctness" of a new neuroscience study/claim based on looking into the associations of the mentioned claims/words in the new study compared to a reference set of thousands of previously published neuroscience papers. The idea here is that there are associations hidden in the vast amount of literature out there that humans in general and singular scientists in particular just cannot read, remember, grasp and comprehend anymore due to the exponential growth in studies. Importantly all thus trained LLMs outperform a large panel of human expert in predicting whether or not a new study or a fake study is true. This is really fascinating and could have major implications to identify new disease MoA hypothesis, target validationa nd dicovery, discover hidden connections and low-hanging treatment option fruits that nobody has yet considered or simply just weed out fake or irrelevant new er publications. #ai #science #neuroscience #drugs #future #LLM #nostr

#bitcoin #nostr #memes

My favorite euphemism from corporate world is "let's take a bio break"

Today, I experienced a first: someone told me they got interested in Bitcoin after reading my book and now plan to buy some. Made my day to know I finally managed to orange pill someone! #bitcoin #books

Another ALS clinical trial failure:

Fierce Biotech

PTC axes utreloxastat program after phase 2 ALS failure

PTC Therapeutics’ amyotrophic lateral sclerosis (ALS) prospect has

Unfortunate but sad reality when it comes to CNS disorders. The problem mostly stems from our fundamental ignorance (in the classical meaning) when it comes to these disorders. We truly mostly still don't understand what is the underlying key mechanism of action that needs correction in order to treat these diseases. #science #als #brain #motorneurons

Are LLMs better doctors? LLM model on its own far outperforms physicians when giving the correct diagnosis. Funny thing is, even when physicians are allowed to use AI as support, their correct diagnosis ratio basically does not increase, indicating a tendency of the physicians to cling to their own diagnosis and ignoring the LLMs advice. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2825395 #ai #science #health

playing around with AI-generating video for scenes from my book. I wanted an intense fight in hotel room between a middle-aged US agent and two Chinese bodyguards. I received a beautiful choreographed modern dance triplet of a Chinese Christopher Walken and two supporting dancers. Long way to go. #ai #art #artstr #books #funny

ok,this is just beautiful #sun #universe #science

There is „Broken Money“, there is "The Bitcoin Standard“ but the most interesting I've so far read about the monetary system is „The Creature from Jekyll Island: A Second Look at the Federal Reserve“ by G. Edward Griffin. I can only encourage every bitcoiner to read it. It is excellently written, very engaging & goes in many ways to the core of what the problem with current fiscal policies and banking system is about. For example, right from the 1st chapter: "The purpose ... was to come to an agreement on the structure and operation of a banking cartel. The goal, as is true with all cartels, was to maximize profits by minimizing competition between members, to make it difficult for new competitors to enter the field, and to utilize the police power of government to enforce the cartel agreement. In more specific terms, it was to create a blueprint for the Federal Reserve System. Here were representatives of the world's leading banking consortia... driven together by one overriding desire to fight their common enemy. The enemy was competition. Competition also was coming from a new trend in industry to finance future growth out of profits rather than from borrowed capital…between 1900 and 1910, seventy per cent of the funding for American corporate growth was generated internally, making industry increasingly independent of the banks.... What the bankers wanted … was to intervene in the free market and tip the balance of interest rates downward, to favor debt over thrift. To accomplish this, the money supply simply had to be disconnected from gold and made more plentiful … ." This is just from the 1st chapter and it continues to be enlightning and revealing. In my view it shows even better than Lyn's or Saif's books how the creation of the debt-based money supply system, the creation of the FED and the move away from the gold-standard was not a natural development that simply had to occur for a modern society to function but was instead driven by the influence of a few conspiratory bankers. #nostr #bitcoin #books #bookstr #money

Goodreads

The Creature from Jekyll Island: A Second Look at the F…

Where does money come from? Where does it go? Who makes…

quite interesting and promising results for a potential new therapy for diabetes 2 patients. "Remarkably, at the 6- and 12-month follow-up, 86% of participants (12 out of 14) no longer required insulin therapy, and this success continued through the 24-month follow-up. In these cases, all patients maintained glycaemic control, with HbA1c levels remaining below 7.5%."

Novel procedure combined with semaglutide may eliminate insulin dependency in type 2 diabetes

Novel procedure combined with semaglutide may eliminate insulin dependency in type 2 diabetes

#science #diabetes