The literal meaning is "to choose" but a more contextually accurate translation for its technical use would be "to innovate." It's making a new choice, apart from conventional wisdom or God's law.
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It's well known for at least 30 years now that aspartame influence on alzheimer and other neurological diseases. Not on rats ... on humans. They still sell it today, they don't care.
U.S. Right to Know
Aspartame: Decades of Science Point to Serious Health Risks
The world's most popular sugar substitute has been linked to cancer, cardiovascular disease, Alzheimer’s disease, seizures, stroke, and weig...