Let's go!
Also, keep in mind that some clients are coding an extended version of NIP-44 for bigger payloads: 
GitHub
allow NIP-44 to encrypt more than 65535 bytes by fiatjaf · Pull Request #1907 · nostr-protocol/nips
This is backwards-compatible and no one has to change anything if they do not care about bigger messages.
The only reasonable case where this neces...