Nah, even the most mundane #tags get a ton of crypto content, misogyny, racism, full on Nazis... A good client like Amethyst can pre-filter some of the worst, but step one of nostr for anyone who isn't into crypto and isn't a hateful asshole is to develop an extensive block list.

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Simple tags like #memes can attract it with too much regularity. The more extreme it is, the less common, but the more tame stuff still isn't exactly uncommon. Maybe I just have poor relays configured, but that isn't really a good answer because there's no easy to find information on choosing good relays, probably because it's such an evolving topic.