I've been working with supplements for over 15 years.
I would attribute placebo to being more effective than most supplements. But if it works, it works - as long as the compound isn't causing harm.
One recent example is a handful of customers swore a product was less effective when we moved it into a smaller capsule and eliminated all excipients. If anything it should be marginally more effective, but a couple people even went as far as to suggest the lack of a completely inert filler was the reason why they felt it wasn't working as well. Completely ridiculous.
I've been suing Maya and 3DSMax casually for 2 decades. Not an expert, just enough to fulfil my needs.
Never seen an open world map, like that in a game, modelled on anything but a flat plane. ๐