and when things are tough, "just say good" -jocko
Dan Ostermayer
ostermayer@primal.net
npub1gc64...uyek
physician
metabolic health maximalist
📚
co-sleeping
https://a.co/d/0itAvPV
the simple world
https://a.co/d/5u4BdMU
📚
stay hard everyone
build that physical grit so you can show more emotional strength
fixed some formatting issues. metabolic health labs and ranges
Core Metabolic & Glucose:
1. Fasting Insulin: < 5 µIU/mL (Optimal); Conventional "normal" often up to 25 µIU/mL.
2. Hemoglobin A1c (HbA1c): < 5.3%(Optimal); Conventional "normal" < 5.7%.
3. Fasting Glucose: 70-90 mg/dL.
Lipids & Cardiovascular:
1. Triglycerides: < 80 mg/dL (Optimal); Ideally 50-70 mg/dL.
2. HDL Cholesterol: > 60 mg/dL (Men), > 70 mg/dL (Women) (Optimal).
3. LDL Cholesterol: Context-dependent(Focuses more on particle number/size if concerned, but prioritizes low Trigs/High HDL).
4. Triglyceride/HDL Ratio: < 1.0(Optimal Insulin Sensitivity Marker); < 2.0 is good.
5. Lipoprotein(a) Lp(a): < 30 mg/dL(Lower is better, strong genetic risk factor).
6. Gamma-Glutamyl Transferase (GGT): < 20 U/L (Optimal Liver/Stress Marker); Conventional normal often up to 40-60 U/L.
Hormones:
1. Free T3 (Thyroid): 3.5 - 4.5 pg/mL(Upper half of range optimal for energy/metabolism).
2. Reverse T3 (rT3): < 20 ng/dL(Optimal); High levels indicate stress/conversion issues.
3. TSH: 0.5 - 2.0 µIU/mL (Optimal Function); Conventional normal often up to 4.5-5.0.
4. Total Testosterone (Men): 700 - 1100 ng/dL
5. Free Testosterone (Men): > 20 pg/mL .
6. Estradiol (Men): 20 - 30 pg/mL
7. Cortisol (AM): 12 - 18 µg/dL (Optimal morning peak).
8. DHEA-S (Men): > 350 µg/dL (Optimal for age); Women: Age-adjusted, often > 150 µg/dL.
9. Cortisol:DHEA-S Ratio: < 5x the multiplier (e.g., Cortisol 15 µg/dL / 10. DHEA-S 300 µg/dL = 0.05, which is good). Lower ratio indicates better stress resilience.
Inflammation & Nutrients:
1. High-sensitivity CRP (hsCRP): < 0.5 mg/L (Optimal/Low Inflammation); < 1.0 mg/L good.
2. Homocysteine: < 8 µmol/L (Optimal); Conventional normal often up to 15 µmol/L.
3. Vitamin D (25-OH): 60 - 80 ng/mL(Optimal Immune/Function); Conventional > 30 ng/mL.
4. Magnesium (RBC): > 6.0 mg/dL(Optimal Cellular Status); Conventional serum normal often lower (1.8-2.6 mg/dL).
5. Uric Acid: < 5.5 mg/dL (Men), < 4.5 mg/dL (Women) (Lower end optimal, especially on high-purine diets).
Other Key Markers:
1. Parathyroid Hormone (PTH): 15 - 30 pg/mL (Optimal, indicates good Vit D/Ca status); High levels suggest deficiency/stress.
2. IGF-1: Context-dependent (Moderate levels associated with longevity; very high may link to cancer risk).
3. ALT/AST (Liver Enzymes): < 20 U/L### Ratios
Ratios:
1. Triglycerides/HDL Ratio: < 1.0 (Gold Standard for Insulin Sensitivity).
2. Cortisol/DHEA-S Ratio: Lower is better (Marker of HPA Axis Resilience).
there is a great summary of core metabolic health labs and their appropriate ranges
Core Metabolic & Glucose:
1. Fasting Insulin: < 5 µIU/mL (Optimal); Conventional "normal" often up to 25 µIU/mL.
2. Hemoglobin A1c (HbA1c): < 5.3%(Optimal); Conventional "normal" < 5.7%.
3. Fasting Glucose: 70-90 mg/dL(Optimal Stability).
Lipids & Cardiovascular
1. Triglycerides: < 80 mg/dL (Optimal); Ideally 50-70 mg/dL.
2. HDL Cholesterol: > 60 mg/dL (Men), > 70 mg/dL (Women) (Optimal).
3. LDL Cholesterol: Context-dependent(Focuses more on particle number/size if concerned, but prioritizes low Trigs/High HDL).
4. Triglyceride/HDL Ratio: < 1.0(Optimal Insulin Sensitivity Marker); < 2.0 is good.
5. Lipoprotein(a) Lp(a): < 30 mg/dL(Lower is better, strong genetic risk factor).
6. Gamma-Glutamyl Transferase (GGT): < 20 U/L (Optimal Liver/Stress Marker); Conventional normal often up to 40-60 U/L.
Hormones
1. Free T3 (Thyroid): 3.5 - 4.5 pg/mL(Upper half of range optimal for energy/metabolism).
2. Reverse T3 (rT3): < 20 ng/dL(Optimal); High levels indicate stress/conversion issues.
3. TSH: 0.5 - 2.0 µIU/mL (Optimal Function); Conventional normal often up to 4.5-5.0.
4. Total Testosterone (Men): 700 - 1100 ng/dL (Optimal for vitality); (Reported his own drop to ~500 ng/dL on strict carnivore as suboptimal).
5. Free Testosterone (Men): > 20 pg/mL (Upper end of range optimal).
6. Estradiol (Men): 20 - 30 pg/mL(Balanced range).
7. Cortisol (AM): 12 - 18 µg/dL (Optimal morning peak).
8. DHEA-S (Men): > 350 µg/dL (Optimal for age); Women: Age-adjusted, often > 150 µg/dL.
9. Cortisol:DHEA-S Ratio: < 5x the multiplier (e.g., Cortisol 15 µg/dL / 10. DHEA-S 300 µg/dL = 0.05, which is good). Lower ratio indicates better stress resilience.
Inflammation & Nutrients
1. High-sensitivity CRP (hsCRP): < 0.5 mg/L (Optimal/Low Inflammation); < 1.0 mg/L good.
2. Homocysteine: < 8 µmol/L (Optimal); Conventional normal often up to 15 µmol/L.
3. Vitamin D (25-OH): 60 - 80 ng/mL(Optimal Immune/Function)
4. Magnesium (RBC): > 6.0 mg/dL(Optimal Cellular Status); Conventional serum normal often lower (1.8-2.6 mg/dL).
5. Uric Acid: < 5.5 mg/dL (Men), < 4.5 mg/dL (Women) (Lower end optimal, especially on high-purine diets).
Other Key Markers:
1. Parathyroid Hormone (PTH): 15 - 30 pg/mL (Optimal, indicates good Vit D/Ca status); High levels suggest deficiency/stress.
2. IGF-1: Context-dependent (Moderate levels associated with longevity; very high may link to cancer risk).
3. ALT/AST (Liver Enzymes): < 20 U/L### Ratios
Ratios:
1. Triglycerides/HDL Ratio: < 1.0 (Gold Standard for Insulin Sensitivity).
2. Cortisol/DHEA-S Ratio: Lower is better (Marker of HPA Axis Resilience).
in the US, in many states, you can just order your own labs and interpret them yourselves. the medical knowledge is widely available for most people to read and understand without a medical degree.
(no affiliation)
Walk-In Lab
Order Any Lab Test or Blood Tests Online | Walk-In Lab
Order blood tests online with or without insurance or doctor visit. Walk-In Lab offers direct access to cheap blood work and lab testing with secur...
public health is based on the principle of utilitarianism with the greatest good for the greatest number of people
the opposite of that is private health, the optimization of your own body for your own good for your own longevity and health maximization
people report the benefits of carnivore diets because they are generally increasing their protein intake and at the same time eliminating garbage food.
by no means is carnivore diet consistent with our evolution but it is a great diet to cleanse your system of a lifetime of toxins
One of the biggest expenses for small to medium size medical practices are electronic health record software. Many of them have expensive licenses and lock-in. The HiTech act in 2009 made usage of them essentially mandatory or you would get decreased reimbursement and penalties.
If have a medical practice that does not bill insurance that only accepts cash, you can use any type of documentation software you want without needing to use any of the Medicare Medicaid approved billing software.
Animal Based Nutrition Research Foundation salt testing results

ABNRF Salt Study - Here’s What We Found
We conducted independent lab testing on seven popular salts to see what’s really inside. Our results show that some contain measurable levels of ...

the Surgery Center of Oklahoma is a legend in its ability to create a high quality institution that is cash only healthcare. here is a video of the founder Dr. Keith Smith speaking about fixing costs in the united states
this will help many dental, vets and small medical practices
View quoted note →
good overview of cancer growth accelerated by high fructose corn syrup


Excess Fructose May Fuel Obesity, Colorectal Cancer Growth
Excess consumption of fructose can promote both obesity and colorectal cancer, a new study shows. Conducted largely in mice, the study found that a...
this is just a taste of what a self hosted AI can do.
1. record with a transcript your answers to these 1000 questions
https://savewisdom.org/wp-content/uploads/2025/02/SaveWisdomQuestions-NEW-1.pdf
2. load up deep seek or oss-gpt on lmstudio on your own computer
3. feed the model your answers from step 1.
4. ask the llm to provide insight to a question using the thought process from your 1000 questions.
5. imagine a future where your children can interact with a model of you when you are gone
LMStudio is the most user friendly privacy focused ai tool for text based analysis and allows for apple silicon (mlx) optimized open source models
if you need to parse and format moderate to large data sets it is wonderful.
not sure how i missed this, but aeropress is now making a metal and glass version of the best coffee maker on the planet.
i have the old plastic one and always worried about the possibility of microplastics


AeroPress
AeroPress Coffee Maker - Premium
Discover the AeroPress Premium Coffee Maker, crafted from elegant double wall borosilicate glass, stainless steel and anodized aluminum. Elevate yo...
biology follows the power law for metabolism
The heart grows proportionally with the rest of the body while the head grows early in life, reaches a certain size, and stops growing. This suggests that head growth is subject to very different growth conditions compared to the heart. One hypothesis for this difference is that if the relationship between two variables displays a log-log relationship
I hypothesis that this is due to the power law relationship of eukaryotic mitochondria

Application of Power Laws to Biology : Networks Course blog for INFO 2040/CS 2850/Econ 2040/SOC 2090
Universal dynamics of mitochondrial networks: a finite-size scaling analysis - PMC
Evidence from models and experiments suggests that the networked structure observed in mitochondria emerges at the critical point of a phase transi...

try and cultivate a miniature version of reality for your kids based on what they can handle and might be able to handle.
then they will be ready for reality when an adult
your mitochondria love serotonin.
we are slowly learning that metabolic health via mitochondrial health is at the root of mental health issues
SSRIs don't really cure depression but they do act on your mitochondria and encourage the usage of oxygen for ATP synthesis which gives your brain greater amounts of available energy so you are less depressed.
Serotonin minting new mitochondria in cortical neurons: implications for psychopathology - PMC