Dan Ostermayer's avatar
Dan Ostermayer
ostermayer@primal.net
npub1gc64...uyek
physician metabolic health maximalist ๐Ÿ“š co-sleeping https://a.co/d/0itAvPV the simple world https://a.co/d/5u4BdMU ๐Ÿ“š
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ostermayer 6 months ago
we now have the published results from the viral control study group "Cell cultures were split into two distinct paths, differing only by the concentration of fetal bovine serum (FBS) in the growth medium (Medium 1 with 10% FBS vs. Medium 2 with 2% FBS)." --> when you starve cells the nutrients they need they produce particles that look eerily similar to viruses image
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ostermayer 6 months ago
people report the benefits of carnivore diets because they are generally increasing their protein intake and at the same time eliminating garbage food. by no means is carnivore diet consistent with our evolution but it is a great diet to cleanse your system of a lifetime of toxins
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ostermayer 7 months ago
average cost of a familyโ€™s annual health insurance premium has jumped +6% YoY in 2025, to $27,000, an all-time high. This marks the 3rd consecutive annual increase, following 2023 and 2024 gains of +7%. In other words, premiums are now rising faster than inflation for the 3rd year straight. Since 2000, the average health insurance premium has surged +350%. Small businesses are seeing the largest health-rate increases, with over half reporting +10% or more premium hikes in 2025. image
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ostermayer 7 months ago
grass fed cows make butter that is more yellow than cows fed corn etc. The yellow color is from the beta-carotene content which our body uses to make vitamin A. image
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ostermayer 7 months ago
Dan Ostermayer's avatar
ostermayer 7 months ago
There unfortunately are no double blind randomized placebo controlled trials in clinical vaccine research. All of the trials use an "active" placebo for good reason. The adjuvent is probably the problem for humans not the innactivated dna/rna particle. Here is a list of placebos for vaccine trials: 1. HPV (Gardasil) Clinical Trial: Placebo was an aluminum adjuvant and the Hepatitis A vaccine. 2. Hepatitis A Clinical Trial: Placebo was the Hepatitis B vaccine. 3. Influenza A Clinical Trial: Placebo was the Influenza B vaccine. 4. Meningitis Vaccine Clinical Trial: Placebo was the DTaP (Diphtheria, Tetanus, and Pertussis) vaccine. 5. Pertussis Vaccine Clinical Trial: Placebo was the Diphtheria & Tetanus vaccine. 6. Prevnar-13 (Pneumonia) Clinical Trial: Placebo was the Prevnar-7 vaccine. 7. Hepatitis A Clinical Trial: Placebo was an aluminum adjuvant. 8. Prevnar-9 (Pneumonia) Clinical Trial: Placebo was the DTP-Hib vaccine. 9. Cholera Vaccine Clinical Trial: Placebo was the K-12 E.Coli vaccine. 10. Prevnar-23 (Pneumonia) Vaccine: Placebo was the Hepatitis A & B vaccines. 11. Polio Vaccine Clinical Trial: Placebo was a diluted polio vaccine. 12. Chicken Pox Vaccine Clinical Trial: Placebo was a diluted chicken pox vaccine. 13. Shingles Vaccine Clinical Trial: Placebo was a diluted shingles vaccine. 14. Some COVID-19 Vaccine Clinical Trials: Placebo was the Meningitis vaccine.
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ostermayer 7 months ago
the online thing that matters in any scientific field, is the release of data. in physics a researcher does an experiment, explains the protocol writes very little about the results and releases the data which speaks for itself. in health sciences the opposite occurs. we describe the population/protocol, keep the data private, and then write endlessly about the statistical corrections necessary for interpretation. researchers should simple release all clinical data all the time for even the most trivial of retrospective studies (positive or negative). we don't need new journals, we need data repositories with attached data collection protocols. View quoted note โ†’
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ostermayer 7 months ago
in clinical research there are so many observational studies that could be published if clinicians could structure all of their unstructured data. The retrieval-augmented generation (RAG) of LLMs finally allows for easy means of querying big sets of clinical text and results.
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ostermayer 7 months ago
most vitamin D3 (cholecalciferol) capsules are semisynthetic it is extracted from lanolin (sheep's wool). The lanolin contains 7-dehydrocholesterol, which is then exposed to UV light to convert it into Vitamin D3 (cholecalciferol) Some "vegan" Vitamin D2 (ergocalciferol) supplements are produced by exposing lichens to ultraviolet light. humans can store vitamin d in adipose tissue (fat soluble) for indefinite periods of time. The more time you get in the sun during the summertime the less likely you are to need any vitamin d in the winter regardless of where you live on the planet. image
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ostermayer 8 months ago
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ostermayer 8 months ago
pretty tough to find raw milk in the US but very easy to find italian parmesan reggiano which is basically portable raw milk image
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ostermayer 8 months ago
I made this table for a family member who was trying to convince me the need to take a multivitamin. At worst you just urinate out the excess vitamins that are water soluble if you don't need them. However, I'd rather spend money on food than vitamins. It is very easy to get all of your micro-nutrients from animal based diets. Also easy as a carnivore as well but not necessary to be that restrictive.
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ostermayer 8 months ago
The value of intermittent fasting is probably grossly over exaggerated once you get down to a body fat percent of less than 15%
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ostermayer 8 months ago
weighted pull ups over time have put too much stress on my wrist and metacarpals. using these pull up hooks have solved those issues so i can do 50lb weighted pull ups x5 without any injuries.
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ostermayer 8 months ago
co-sleeping is one of the most important activities a mother can do with their newborn and infant. image
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ostermayer 8 months ago
Evidence-Based Health Benefits of Bovine Colostrum 1. Gastro-Intestinal Health: Enhanced gut barrier integrity: Bovine colostrum supplementation (+20 g/day) significantly reduces intestinal permeability (Leaky-Gut index) in both healthy adults and athletes, evidenced by lower urinary lactulose/rhamnose ratios [1] Protection against NSAID-induced damage: In human volunteers given indomethacin, 125 mL colostrum (3ร— daily) preserved GI sucrose permeability and maintained villous height/architecture compared to control [2] Enhanced recovery after gut injury: Following NSAID-induced enteropathy, 8-week colostrum intake (500 mg bovine IgG concentrate) improved small-bowel villous surface area and gut microbiome diversity [3] 2. Immune Modulation: Upper-respiratory tract infection (URTI) prevention: Athletes in heavy training who consumed 10 g/day bovine colostrum showed 45% fewer URTI episodes and 40% reduced symptom days over 8 weeks, along with preserved salivary IgA concentrations [4] Influenza vaccine adjuvant: Healthy adults receiving 400 mg/day of a high-IgG colostrum capsule alongside flu vaccination produced 2.7-fold higher hemagglutinin-inhibition titers at 6โ€“8 weeks [5] Auto-regulation of inflammatory cytokines: Milk-derived bovine-colostrum protein isolate reduced serum TNF-ฮฑ and IL-6 in patients with IBD while improving disease activity indices (HBI / SCCAI) [6] 3. Exercise Performance & Recovery: Improved incremental shuttle-run time: Eight weeks of 20 g/day bovine colostrum raised distance covered from 1325 m to 1420 m (+7 % ฮ”) vs. whey placebo in elite female soccer players [7] Faster CK recovery post-exercise: Following 30 km downhill running, colostrum (60 g/day) lowered peak plasma CK by โ‰ˆ31 % and DOMS scores by 1โ€“2 points versus control, indicating reduced muscle damage [8] 4. Safety & Tolerability: Generally recognized as safe (GRAS): Bovine colostrum powders, provided they are from healthy, pasteurized dairy sources, yield no serious adverse events in >1,000 subjects across reviewed trials (frequency <0.3 %) [9] May trigger milk-protein allergy or lactose intolerance: Use with caution in individuals with documented milk hypersensitivity; lactose concentration (โ‰ˆ2โ€“5 %) is generally well-tolerated by lactose maldigesters when taken with food [10] Suggested Dosing Ranges Used in Human Studies References: [1] Madureira, A. R., et al. Alimentary Pharmacology & Therapeutics, 2020. [2] Playford, R. J., et al. Gut, 1999. [3] Ivanovska, N., et al. Nutrients, 2021. [4] Brinkworth, G. D., & Buckley, J. D. European Journal of Nutrition, 2003. [5] Jones, A. W., et al. Nutrients, 2019. [6] Goehler, L. E., et al. Clinical Nutrition, 2023. [7] Shing, C. M., et al. Medicine & Science in Sports & Exercise, 2006. [8] Davison, Glen. European Journal of Applied Physiology, 2018. [9] van Hooijdonk, A. C. M., et al. Critical Reviews in Food Science and Nutrition, 2022. [10] Saad, K., et al. World Allergy Organization Journal, 2023. image
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ostermayer 8 months ago
if you have kids and they like chicken strips, don't take them to Chick-fil-A. Just buy a big pack of these from costco and let them enjoy some tallow chicken strips. image
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ostermayer 8 months ago
coming over from twitter, it is pretty wild to think i own my identity here. as a doc who was always hesitant to post during covid times since anything against the doctrine could end in a deplatforming event, nostr would have been amazing to have during such a controversial and manipulated timeline. i'll mostly post about metabolic health as it is core to everything. without health it doesn't matter how rich you are.
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ostermayer 8 months ago
most primary care physicians measure your A1c to screen for progression to diabetes but it is an inferior measurement to capture early metabolic dysfunction. They should be measuring fasting insulin levels. Here's why:
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