Dr Sam Soete

One of the most commom presentations I see in clients these days: "I feel like my whole system has been stuck in a constant state of stress, I can’t get my nervous system to calm down or return to a real sense of safety or rest."

The brainstem needs a HUGE amount of energy to function optimally and regulates the processes of the body. If you are dealing with weird symptoms spanning many organ systems, look into the brainstem and energy production.

Centralized medicine is unable to square the idea that malnutrition and obesity can coexist.

Complex disease stemming from impaired energy metabolism cannot be identified or effectively managed in the centralized model of organ-system hyperspecialization. This leads to massive amounts of people being diagnosed and essentially gaslighted with "functional disorder" labels. This model forces an artificual compartmentaluzation of disease/dysfunction = inability to recognize causal factors spanning multiple organ system (such as impaired mitochondrial function leading to low ox phos and dysautonomia).

Pharmaceuticals are one of the most underappreciated group of mitochondrial stressors right now. A large majority of drugs/medications/vaccines damage mitochondria and impair oxidative metabolism. Statins, SSRIs, antibiotics, vaccine (adjuvants), diabetes meds are some of the worst. This iatrogenic harm is still unrecognized for the most part.

Restoration of meaning and a sense of responsibility (others relying on you) is crucial to addressing the mental health crisis in men.

Healing is a function of the body, all it requires is energy

The Nature of Expertise If you want to learn something deeply, the ideal teacher is someone who both understands the subject matter in depth and has firsthand experience applying it. That combination of knowledge & experience constitutes real expertise. Formal qualifications may signal exposure to centralized knowledge, but they are not a prerequisite for genuine understanding. A person can develop deep expertise through independent study, experimentation, mentorship, and persistent curiosity. What matters most is the depth of comprehension and the ability to apply knowledge critically, not the possession of a credential. When combined with discernment, critical thinking, and humility, the modern learner has access to nearly all the tools once monopolized by centralized institutions (books, research archives, open discussions, and the global reach of the internet). Given enough time, discipline, and feedback, a dedicated individual can cultivate legitimate expertise without ever stepping into a traditional institution. That said, foundational learning often benefits from structured environments. Institutions, when well-run, provide frameworks that help students grasp fundamentals efficiently, expose them to peer discourse, and offer curated access to expert feedback. They also encourage curious pursuit of unanswered questions - that is the beauty of University (the philosophy, not the institution). This scaffolding can prevent blind spots that self-taught learners sometimes develop when they lack structure or guidance. Or skipping foudational concepts leading to a shakey base. Therefore, in a decentralized soace, it is crucial to constantly test models of understanding with peers (nodes), and relinguish any resemblance of hubris or arrogance. However, centralized institutions are not without flaws. Their bureaucratic structure often makes them slow to update models of reality, resistant to paradigm shifts, and vulnerable to perverse incentives - whether financial, political, or reputational. A certificate, at its core, is evidence that someone has completed a prescribed course of study within that system. It is not necessarily proof of wisdom, creativity, or the capacity to think independently. If someone dismisses an individual due to a lack of credentials without addressing their ideas or refuting their model, something nefarious is going on. There is no excuse for this. In truth, most knowledge is not locked behind institutional walls. What they primarily offer is organization and access to mentors. The development of expertise likely requires a balance of both worlds. Centralized structure and guidance, and Decentralized paradigm shifts and ruthless questioning.

B1 plays a role in the de novo synthesis of neurotransmitters (from glucose) including acetylcholine and glutamate. The pyruvate dehydrogenase complex (which requires B1) makes acetyl-CoA which can act as a precursor for acetylcholine. B1 seems to also be involved in ACh release & signalling. Acetylcholine esterase inhibitors are currently prescribed for Alzheimer's. Interesting stuff.

"steady and unhurried, but always in motion." "slow is smooth, smooth is fast"

You have more autonomy over your life than you think (if only one adopts the responsibility for it) And as you extend the timeframe from days to months to years - that autonomy increases. Modernity likes to psyop you into thinking you cant do anythujg about your current circumstances. You have to uncivilize yourself to come to this realisation.

I think you want to spend at least one day a week exposed to natural sunlight throughout the ENTIRE day from sunrise to sunset (does not have to be direct). Ideally its everyday, but that is not feasible for most.

Nature doesn't care about convenience.

The irony is that nutrient deficiency is quite common in obese populations. This is high-calorie malnutrition and it leads to impaired energy production at the mitochondrial level resukting in a cascade of cellular -> tissue -> organ dysfunction.

Insulin Resistance = Mitochindrial Dysfunction

Another beauty Gm

Optimising Immunity > Avoiding Pathogens The former develops courage and capability, the later breeds fear and weakness.

Centralised Medicine = Ptolemaic world view Decentralised Health = Copernican world view

Don't let people manipulate you with cherry-picked data. Before the 1960s, most children contracted measles, and in developed countries, complications were rare. Healthy children typically recovered without issues. However, measles can be dangerous in malnourished children in developing nations or in populations newly exposed to the virus. Vitamin A & D status is incredibly important. Research suggests children who recover from measles between ages 4-7 may have lower rates of heart disease later in life (Kubota Y, Iso H, et al). An interesting association potentially relating to immune maturation. Infants under one year are at highest risk for severe measles, but maternal antibodies from breastmilk provide passive immunity if the mother had natural measles. Historically, measles mortality dropped sharply before the vaccine due to better nutrition, living conditions, and medical care. Measles parties and vitamin A (cod liver oil) were common preventive measures. Severe measles cases in children are often linked to vitamin A deficiency. High-dose vitamin A supplementation during measles infection significantly reduces complications and mortality.

The answer is yes.