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You will be given a vitamin D supplement, which will raise your LDL, then they will give you a statin, which will impair your mitochondria, then you will be given metformin, duloxetine or pregabalin, and on the cycle goes. Really, all you needed was some sun.

We are scared of the wrong things. We fear alienation. We fear not fitting in. We fear criticism, embarrassment and failure. How about the idea that we have less than 5000 weeks on this earth? 5000 weeks to do something worthy of the gift of life. This is the way.

What happens to your ability to uncouple your mitochondria and burn of excess calories or regulate temperature when you are on statins and develop a CoQ10 deficiency?

𝗠𝗶𝘁𝗼𝗰𝗵𝗼𝗻𝗱𝗿𝗶𝗮 𝘄𝗶𝗹𝗹 𝘄𝗼𝗿𝗸 𝘀𝘂𝗯-𝗼𝗽𝘁𝗶𝗺𝗮𝗹𝗹𝘆 𝗶𝗳: 1. They receive the wrong fuel (light & food mismatch) 2. Are deficient in key building blocks (CoQ10, B vitamins, Mg, Cu, Zn, Se, fats, etc.) 3. Inhibited by toxins (antibiotics, heavy metals etc.) 4. Levers pulling on mitochondrial function are impaired (thyroid function for example)

No words needed.

Butyrate is a mitochondrial nutrient. But its never mentioned alongside CoQ10, PQQ, B vitamins, etc. 1) Direct fuel source Colonocytes preferentially use it as their main energy substrate. Butyrate enters mitochondria and undergoes β-oxidation → acetyl-CoA → TCA cycle → ATP. Brr.. Very nice. 2) Epigenetic regulation Butyrate inhibits histone deacetylases or HDACs. Learnt this from mr Greg. This changes gene expression in ways that upregulate mitochondrial biogenesis (via PGC-1α, NRF1/2) and antioxidant defenses. 3. Redox balance Butyrate metabolism increases NADH and FADH2 supply to the ETC. 4. Anti-inflammatory signaling Really interested in this one regards to CDR. By dampening NF-KB and upregulating Nrf2 pathways, it reduces chronic inflammation and returns mitochondrial prioritisation to energy production. 5. Mitochondrial quality control Butyrate might also promote mitophagy and fusion/fission dynamics so that lowers heteroplasmy.

Things that are basically NEVER mentioned in medical school: - Anything regarding light - Circadian biology - Importance of mitochondria - Biophysics of water - Toxins (xenoestrogens, glyphosate, heavy metals) - Importance of micronutrients

Sun = ↓ Heart Disease ↓ Stroke ↓ High Blood Pressure ↓ Type 2 Diabetes ↓ Obesity ↓ Fatty Liver Disease ↓ Cancer ↓ Dementia ↓ Autoimmune Disease ↓ Multiple Sclerosis ↓ Type 1 Diabetes ↓ Rheumatoid Arthritis ↓ Infections ↓ Depression ↓ Anxiety ↓ Addiction ↓ Chronic Pain ↓ Bone Fractures ↓ Osteoarthritis ↓ Hormone Dysregulation ↓ Insomnia ↓ Sleep Apnea ↓ Eczema ↓ Psoriasis But maybe, if you are an idiot, you will have more wrinkles when you are 60?

Could disconnecting from the Earth's electrical field play a role in chronic disease prevalence? 🤔 Shoe sales vs Diabetes growth

If you restore energy production you would be surprised at the health issues your body can resolve on its own

Balanced sunlight exposure increases vagal tone while artificial light reduces it. People underestimate the consequences of this. Vagal tone reprograms the immune system to facilitate anti-inflammatory, pro-resolving functions which has profound effects on all chronic-disease states as well as neuropsychiatric issues like generalized anxiety, obsessive thoughts, PTSD etc.

Okay my goal is to become the top decentralised doctor on Nostr. Let's run it.

All chronic diseases have issues with cellular bioenergetics at their core. Mitochondrial dysfunction is the linchpin underlying all of this. Cardiovascular diseases, cancers, chronic respiratory diseases, diabetes, etc. If you want to optimise your health you have to start with your mitochondria. This is what decentralised health optimisation is about.

Your mitochondria love novelty. Cold water, sunset views, hikes, unexpected challenges, they all signal growth in a functioning anti-fragile system. Side-quest maxxing is mitochondrial hormesis.

Are you not entertained?

Many people have functional deficiencies that are being overlooked by only focusing on absolute deficiencies in their labs. Great thing about metabolomics testing is that the imbalances often tell you about functional deficiencies. Intake is one thing. Absorption is another. Then there is assimilation, utilisation, depletion and potential blockages to enzymatic activity (& genetics) as well.

𝗟𝗶𝗴𝗵𝘁 𝗶𝘀 𝗻𝗼𝘁 𝘀𝘁𝗮𝘁𝗶𝗰. 𝗜𝘁 𝗰𝗵𝗮𝗻𝗴𝗲𝘀 𝘁𝗵𝗿𝗼𝘂𝗴𝗵𝗼𝘂𝘁 𝘁𝗵𝗲 𝗱𝗮𝘆 𝗶𝗻 𝗮 𝘄𝗮𝘆 𝘁𝗵𝗮𝘁 𝗽𝗿𝗼𝗳𝗼𝘂𝗻𝗱𝗹𝘆 𝗶𝗻𝗳𝗹𝘂𝗲𝗻𝗰𝗲𝘀 𝗵𝘂𝗺𝗮𝗻 𝗯𝗶𝗼𝗹𝗼𝗴𝘆. Understanding these changes and how they compare to artificial light sources is key to optimizing your health. Using spectrometry, we can observe these shifts and see why early morning natural light exposure is crucial for synchronizing our internal clocks. At sunrise, the intensity of blue light rapidly increases, reaching the same level as red and near-infrared light. UVA first enters the spectrum of light we receive when the sun is roughly 10 degrees above the horizon. And the UVB rise takes place at 30 degrees. During solar noon peak, the blue portion of the spectrum becomes dominant. At this time, blue light intensity surpasses other wavelengths, acting as a powerful daytime signal to the body. This reinforces wakefulness, cognitive alertness, and metabolic function. This is why you want to get outside as often as possible throughout the day, to give your mitochondrial colony & physiological systems the accurate inputs it requires to function optimally.

Can T levels predict trading profitability? Testosterone level (+ androgenic metabolites) and risk-taking have a bidirectional relationship. So in a bull market, where it pays to put more risk on the table (sensibly), it may be beneficial to have higher T levels. There are actually some studies on this as well. - Traders with higher 11:00 a.m. testosterone levels made significantly greater profits for the rest of the day. - Days with above-median morning testosterone yielded 25% higher profits on average. - Testosterone rose on days when traders exceeded their monthly average P&L. - This suggests a "winner effect," where success boosts testosterone, potentially encouraging further risk-taking. Is there a wealth transfer occurring from low T to high T men?

Why is vitamin B1 key for gut health? B1 ➜ Acetylcholine synthesis ➜ Vagus nerve ➜ Parasympathetic tone. This leads to: - Increased blood flow to the gut - Digestive enzyme secretion - Improved motility via MMC - Reduced inflammation - Reduced intestinal permeability