My testosterone was 1138ng/dl (2024, retesting soon). *Yes I will actually show you some receipts. So what do I do? - Optimize sleep (9pm-5am +1-2hrs in winter) - Maximised sunlight exposure especially UV - Kept my circadian rhythms in sync - Micronutrient dense diet (animal based) - Exercised consistently - Built a healthy amount of lean muscle mass - Avoided xenoestrogens as much as possible - Daily grounding as much as possible - Believed in my often contrarian viewpoints despite mainstream ideology The fundamentals are what matter. Always. This is the way.

Visual anagrams. Coolest thing I've seen today .

If you don't make beta endorphins from the sun and moving your body, it will seek opioid substances elsewhere.

Thiamine requires magnesium to be activated to TPP.

Drivers of Thiamine Deficiency 1. Dietary Choices - Refined sugar and carbohydrates - White rice intake (polished rice) - Processed foods - Frequent alcohol consumption 2. Poor Absorption - Chronic gut issues (SIBO, IBD) - Thiamine inhibitors (coffee, tea, raw fish) - Medications (metformin/ diuretics for example) -General digestive impairment 3. Increased Losses - Kidney disease - Diabetes -Diarrhea or chronic loose stools - Vomiting 4. Increased Demand - Excessive exercise - Surgery or infection - Pregnancy and lactation - Hyperthyroidism - High carbohydrate diet 5. Oxidative Stress - Impaired antioxidant system - Environmental Toxicities

Gm

On the importance of spontaneous curiosity & exploration. "I wonder what's over that hill over there..." "Where does this little path lead to..." When this feeling arises, follow it. Always follow it. Its the path to adventure. Where side quests are found. This is what humans are built for. This is our niche.

The microbiota target mitochondria to regulate their interaction with us. If this signalling is imbalanced that will result in a mito dysfunction -> cellular dysfunction. We know that short chain fatty acids have beneficial effects on mitochondrial activity. Gut health drives healthy mitochondria and the two cannot be separated. This is the holobiont perspective. Systems upon systems.

If you want freedom, you have to take control of your health. It is foundational.

Gm

You will be given a vitamin D supplement, which will raise your LDL, then they will give you a statin, which will impair your mitochondria, then you will be given metformin, duloxetine or pregabalin, and on the cycle goes. Really, all you needed was some sun.

We are scared of the wrong things. We fear alienation. We fear not fitting in. We fear criticism, embarrassment and failure. How about the idea that we have less than 5000 weeks on this earth? 5000 weeks to do something worthy of the gift of life. This is the way.

What happens to your ability to uncouple your mitochondria and burn of excess calories or regulate temperature when you are on statins and develop a CoQ10 deficiency?

Things that are basically NEVER mentioned in medical school: - Anything regarding light - Circadian biology - Importance of mitochondria - Biophysics of water - Toxins (xenoestrogens, glyphosate, heavy metals) - Importance of micronutrients

Sun = ↓ Heart Disease ↓ Stroke ↓ High Blood Pressure ↓ Type 2 Diabetes ↓ Obesity ↓ Fatty Liver Disease ↓ Cancer ↓ Dementia ↓ Autoimmune Disease ↓ Multiple Sclerosis ↓ Type 1 Diabetes ↓ Rheumatoid Arthritis ↓ Infections ↓ Depression ↓ Anxiety ↓ Addiction ↓ Chronic Pain ↓ Bone Fractures ↓ Osteoarthritis ↓ Hormone Dysregulation ↓ Insomnia ↓ Sleep Apnea ↓ Eczema ↓ Psoriasis But maybe, if you are an idiot, you will have more wrinkles when you are 60?

Okay my goal is to become the top decentralised doctor on Nostr. Let's run it.

Are you not entertained?

Many people have functional deficiencies that are being overlooked by only focusing on absolute deficiencies in their labs. Great thing about metabolomics testing is that the imbalances often tell you about functional deficiencies. Intake is one thing. Absorption is another. Then there is assimilation, utilisation, depletion and potential blockages to enzymatic activity (& genetics) as well.

𝗟𝗶𝗴𝗵𝘁 𝗶𝘀 𝗻𝗼𝘁 𝘀𝘁𝗮𝘁𝗶𝗰. 𝗜𝘁 𝗰𝗵𝗮𝗻𝗴𝗲𝘀 𝘁𝗵𝗿𝗼𝘂𝗴𝗵𝗼𝘂𝘁 𝘁𝗵𝗲 𝗱𝗮𝘆 𝗶𝗻 𝗮 𝘄𝗮𝘆 𝘁𝗵𝗮𝘁 𝗽𝗿𝗼𝗳𝗼𝘂𝗻𝗱𝗹𝘆 𝗶𝗻𝗳𝗹𝘂𝗲𝗻𝗰𝗲𝘀 𝗵𝘂𝗺𝗮𝗻 𝗯𝗶𝗼𝗹𝗼𝗴𝘆. Understanding these changes and how they compare to artificial light sources is key to optimizing your health. Using spectrometry, we can observe these shifts and see why early morning natural light exposure is crucial for synchronizing our internal clocks. At sunrise, the intensity of blue light rapidly increases, reaching the same level as red and near-infrared light. UVA first enters the spectrum of light we receive when the sun is roughly 10 degrees above the horizon. And the UVB rise takes place at 30 degrees. During solar noon peak, the blue portion of the spectrum becomes dominant. At this time, blue light intensity surpasses other wavelengths, acting as a powerful daytime signal to the body. This reinforces wakefulness, cognitive alertness, and metabolic function. This is why you want to get outside as often as possible throughout the day, to give your mitochondrial colony & physiological systems the accurate inputs it requires to function optimally.

I like exercising outside. Between sets of pullups/dips/pushups/squats etc, I walk around for a minute or two. If my workout is 20 sets, then that is 40 minutes of walking (5,000 steps) integrated into my workout. Alternatively, Ill do some mobility work between sets. Grounded and in the sun. This is the way.