The irony is that nutrient deficiency is quite common in obese populations. This is high-calorie malnutrition and it leads to impaired energy production at the mitochondrial level resukting in a cascade of cellular -> tissue -> organ dysfunction.

Insulin Resistance = Mitochindrial Dysfunction

Another beauty Gm

Optimising Immunity > Avoiding Pathogens The former develops courage and capability, the later breeds fear and weakness.

Centralised Medicine = Ptolemaic world view Decentralised Health = Copernican world view

Don't let people manipulate you with cherry-picked data. Before the 1960s, most children contracted measles, and in developed countries, complications were rare. Healthy children typically recovered without issues. However, measles can be dangerous in malnourished children in developing nations or in populations newly exposed to the virus. Vitamin A & D status is incredibly important. Research suggests children who recover from measles between ages 4-7 may have lower rates of heart disease later in life (Kubota Y, Iso H, et al). An interesting association potentially relating to immune maturation. Infants under one year are at highest risk for severe measles, but maternal antibodies from breastmilk provide passive immunity if the mother had natural measles. Historically, measles mortality dropped sharply before the vaccine due to better nutrition, living conditions, and medical care. Measles parties and vitamin A (cod liver oil) were common preventive measures. Severe measles cases in children are often linked to vitamin A deficiency. High-dose vitamin A supplementation during measles infection significantly reduces complications and mortality.

The answer is yes.

There is an underappreciated link between fatty liver/NAFLD and gut inflammation/dysbiosis/hyperpermeability. When the intestinal barrier breaks down, bacterial endotoxins enter the portal vein. It drains directly into the liver, so hepatocytes are first exposed to things like LPS. LPS triggers inflammation, ROS, and TNF-alpha release which impairs mitochondrial function. Then there is also the bidirectional link between bileflow and dysbiosis. Ethanol or acetaldehyde produced by certain microbes will overwhelm liver detox pathways. Many people also have a high ammonia burden due to high urease activity in certain bacterial strains -> more pressure on the liver. To the extent that dysbiosis impairs SCFA production, you get further metabolic dysfunction.

Gm

Excessive caffeine use will also deplete B1 status. It reduces B1 absorption & increases B1 wasting at the kidney level. Combine excessive coffee use at work with alcohol consumption after work for long periods of time and you can get into trouble. Not to mention the synergistic requirements of B1 and magnesium.

Magnesium is fundamental to effective vitamin D synthesis and activation. If you can't get your vitamin D status up, look into magnesium repletion.

Gm NOSTR

You don’t get a sunburn through glass because UVB is blocked, but you still get UVA & HEV-driven oxidative damage and collagen breakdown, without the NIR spectrum that normally signals repair and resilience. The protective warning of UVB-induced erythema is gone.

Did you know that farm animals living outdoors don't fatten as easily as those living indoors. 🤔

A study done in 1939 showing the effects of UV light on testosterone. "Exposure of the genital region is more effective than the chest."

Beach reading

Certain local impairments of enzyme function due to localised heavy metal burden for example can create functional nutrient deficiencies in those organs.

Are you bench maxxing anon?

If you are dealing with ANY autoimmune condition, you need to expose yourself to more natural sunlight, especially UV light.

Blessed day.