GM -- I saw Johnson give a talk years before he embarked on his " #longevity quest"... He looked completely different.
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Lots of thoughts about this. 100% respect the "don't die" position, that's been my goal since a very young age. I never wanted to have to go the "ascetic" route as he has, although I respect it as somewhere between scientific self-experimentation and extreme performance art.
I thought (mistakenly in the late 90's and early 00's) atomic #nanotech would advance much quicker than it has, instead most "innovation" funding this century has gone to Bits instead of Atoms.
Despite this, there's always #cryonics, which continues to slowly plod along, which in combination with brain imaging (moving reasonably quickly) and continued advancements in nanotech (still moving slowly but non-zero), could I think produce a decent backup by the time I need it.