the metabolic theory of cancer is starting to catch on
hopefully it because mainstream that the mitochondria is at the heart of cancer development
"no tumor has yet been described with a normal content or composition of cardiolipin, the inner mitochondrial membrane-enriched phospholipid essential for the efficiency of OxPhos function"
most oncologist still treat cancer as a generic disease (a mutation gone wild)
The Warburg hypothesis and the emergence of the mitochondrial metabolic theory of cancer | Journal of Bioenergetics and Biomembranes
Otto Warburg originally proposed that cancer arose from a two-step process. The first step involved a chronic insufficiency of mitochondrial oxidat...
PubMed
Mitochondria and the Metabolic Logic of Oncocytic Tumors - PubMed
Oncocytic tumors represent a compelling model for understanding cancer through the lens of mitochondrial metabolic dysfunction, challenging the pri...