It's funny how daunting it is before you do it and how easy it gets when you realize how much it's just like legos.
I've rebuilt my desktop so many times the only original component left is the case -- a real ship of Theseus. The original build was done with a steak knife because I'd just moved in and didn't have a screwdriver in the apartment 14 years ago.
Hadn't heard of Framework. While I'm not sure I see a need on desktops, someone finally making an accessible laptop case is very welcome, because those things have always been a nightmare.