So again, if we're going to open up the subject of "eminent domain" to be "the entire geographic area of the nation", which is specifically NOT what that means, why don't we just say that the State has "eminent domain" over our brains and therefore the right to restrict drugs? Why don't they have the right to restrict every decision we make on the basis of what it will costs the welfare state?

As for drugs, these are indeed victimless crimes. Laws around them basically amount to pre-crime, based on the heuristic that people who use drugs go on to commit crimes, and therefore, drugs are banned. Statistically it's commonly accurate enough, but it's lazy enforcement I can't get behind. Especially since statistical targeting before a crime is committed is not in any way justified.