I've read and I can say that Thiel's contrasting of "innovation" and "globalization" (the latter being essentially a horizontal reproduction of existing solutions) is insightful. The idea that a true monopoly lies in being the only one capable of doing something (by real skill and not by outing the competitors) is less cynical than it initially seems. And I also liked the reflections on "occult sales" (say you are in just for innovation and so on, and create beautiful things so everyone will want to buy your product even when you haven't announced it as a product).
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Thiel is hardcore, it can be scary