Dan Ostermayer's avatar
Dan Ostermayer
ostermayer@primal.net
npub1gc64...uyek
physician creator of https://deepmarks.org and https://alohak.ai
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ostermayer 2 months ago
a primary motivation for me to build @Deepmarks.org was having a searchable collection of links to pdfs when away from my desktop . now the @Deepmarks.org archiver will create an copy of all my pdf links and store them on our blossom server so i can easily search from my phone
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ostermayer 2 months ago
share your bookmarks with your #nostr web of trust directly from the app image
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ostermayer 2 months ago
the browser extension at @Deepmarks.org are actually useful for more than just signing into nostr apps. they have nwc for zaps, and bookmarking for pages
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ostermayer 3 months ago
legalzoom is on ☠️ watch. i used to pay for business compliance package that helped me know when various state and federal requirements were due. with a few scrapes of federal and state websites your bot becomes an always on compliance department
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ostermayer 3 months ago
open claw becomes incredibly powerful when you have it installed and use searnxg and whoogle for search and use for scraping no need to rely on third parties like firecrawl or get limited by scraping rules from other models
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ostermayer 3 months ago
so much of the web is being blocked off from bots because it is based on attention and advertising and lock in platform metrics. bots don't click on ads and they have no platform loyalty. a bot's measure of success is task completion. any company selling attention is now on death watch. 💀💀💀💀 ps: firecrawl allows for bypass of most bot gates
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ostermayer 3 months ago
for anyone concerned about hantavirus (andes variant) here is what is actually happening: people are getting sick with similar symptoms and when we sequence a mixture of their their genes plus tissue that supposedly has the virus, we see similar genetic sequences. we extrapolate that there is a full viral genome in that sample but it is all just guess work inference. 1. starting material is a mixture of viral fragments and host material 2. there is no well person sampled as a control just sick people 3. they are not reading one full virus molecule from start to finish they take fragments, without directly knowing their full molecular origin, broke those reads into even smaller overlapping substrings called k-mers, and used those k-mers to reconstruct a longer sequence. 4. none of it proves the existence of a full sample in the mixture taken from a patient. 5. reconstructed genome is not the same thing as a directly observed complete viral molecule.
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ostermayer 3 months ago
if you drink diet soda put all your effort into stopping Mossavar-Rahmani Y, Kamensky V, Manson JE, et al. “Artificially Sweetened Beverages and Stroke, Coronary Heart Disease, and All-Cause Mortality in the Women’s Health Initiative.” Stroke, February 14, 2019. DOI: 10.1161/STROKEAHA.118.023100 The cohort was 81,714 postmenopausal women aged 50–79 from the Women’s Health Initiative Observational Study, with a mean follow-up of 11.9 years Compared with women drinking fewer than 1 such beverage per week, those consuming 2+ artificially sweetened drinks per day had a 23% higher risk of any stroke and a 31% higher risk of ischemic stroke from clotting in small brain blood vessels They were also 29% more likely to develop coronary heart disease and had 16% all cause mortality this is an observational study so it is very possible that people drinking diet soda have some other confounder in common causing these issue or it is the ingredients in the soda....
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ostermayer 3 months ago
it's very easy to have open claw act as your real estate agent. all housing listings are public and can be crawled from listing sites. You give the bot your criteria for a house -- you give it a price range and you even give it some other information you want such as geography, close to parks, trails brick vs stone materials, school district etc etc. I find the real utility of claw happens when you give your bot an email account (don't use Gmail. they are very aggressive at blocking bots) Instruct your bot to also dig up historic pricing and comparable sales in the same zip so you get real market pricing. The bot should get the listing agent contact for each house and then send you an email weekly with its research. Call the listing agent to schedule a walkthrough, then as you navigate the buying process use your bot so you can learn when you need to do each part of the buying process and make offers with market research backing your offer. bye bye real estate agent fee of 3-6%
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ostermayer 3 months ago
unfortunately all the good educational-entertainment content for kids is on youtube these days. using youtube means using their algorithm and perpetual recommendation engines where kids never have to stop watching which is obviously bad. to solve this problem our kids wrote down the list of shows they want to watch and get new episodes. open claw using a naming script, yt-dlp, and scheduled tasks to download all episodes from their channels in nice folders that plex can read. openclaw checks weekly for new episodes and gets them. kids now have advertising free plex to watch their favorite channels.
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ostermayer 3 months ago
over and over again, I keep hearing many "elites" complaining that they don't know what is and is not authentically human (because of AI). This is really almost irrelevant to humanity. Never do we care what is authentic or inauthentic if a computer program tells you something that is true and a human tells you something that is false which one is more important? the authentically human falsehood or the truth? truth is the pursuit and the medium which it's conveyed is irrelevant judge everything whether AI generated or human generated under the same standard
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ostermayer 3 months ago
your colon cancer risk (and probabaly other cancer risks) are a product of your microbiome diversity https://aacrjournals.org/cancerres/article/86/7_Supplement/3993/779640/Abstract-3993-Artificial-intelligence-integrated. sticking with my thesis that we create cancer not through our genetic risk but from the environmental impact on our genetics. Colorectal cancer rates in adults under 50 have been rising about 3% per year High-fructose corn syrup and pesticides disrupt the gut microbiome When fructose (especially high high-fructose corn syrup intake) exceeds what the small intestine can absorb (roughly a daily soda’s worth), fructose spills into the colon Glyphosate and related agricultural chemicals act like low-dose antibiotics on gut bacteria. They preferentially knock out protective species (Lactobacillus, Bifidobacterium) while sparing pro-inflammatory ones, reducing production of butyrate and other short-chain fatty acids that normally protect the colon lining. Human genetics haven’t changed in 30 years, but the microbiome of someone born in 1990 has been marinating in fructose and pesticide residue since infancy in a way someone born in 1950 never was. If the microbiome is the mediator between modern exposures and tumor biology (as this study suggests) it helps explain why a cancer that used to belong to grandparents is now showing up in their grandchildren. image
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ostermayer 3 months ago
had openclaw with opus 4.7 create a book recommendation engine based on my prior likes and dislikes across 100 books. its first recommendation "red mars" by kim stanley robinson. so far excellent.
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ostermayer 4 months ago
conversation with a friend today: Friend: Dude, have you heard of STRC!? Me: Yea Friend: It's incredible, as long as MSTR can sell their shares I can earn 11% Me: Why can they keep selling shares? Friend: Because they are backed by bitcoin. Me: So as long as bitcoin goes up long term you get 11% forever. Friend: Yeah! Me: So why not just buy bitcoin like Saylor? Friend: 🤔
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ostermayer 4 months ago
most people afraid of raw milk are not afraid to eat parmigiano reggiano cheese
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ostermayer 4 months ago
"Insulin resistance" is one of the most used terms in medicine and also one of the least precise When we say "insulin resistance," we're treating it like a single thing. Insulin does dozens of things in your body. In any given tissue, some insulin-signaling pathways can be impaired while others remain intact. In the liver: hyperinsulinemia drives lipogenesis (making fat) while simultaneously failing to suppress gluconeogenesis (making glucose). The same hormone in the same organ creates two dysfunctional outcomes. In skeletal muscle when fat builds up inside the muscle cells this then blocks the signal insulin uses to tell your muscles ", take in this sugar from the blood." This happens before liver dysfunction In your fat tissue, the problem is basically chronic, low-grade inflammation. When fat cells get overloaded, your immune system treats them almost like an injury and prevents insulin from appropriately releasing fat. Fat cells keep storing sugars as fat but slowly leak the fatty acids back out into the blood even when insulin is high. In the brain, when insulin reaches neurons, it helps tell your brain: "You've eaten you can stop feeling hungry now". The hypothalamus controls this and still gets the signal but can't pass it along properly due to PI3K signaling impairment. In all cases, insulin is the messenger molecule and still gets to its destination properly but all other mechanisms that originate from the insulin signal become dysfunctional. https://pubmed.ncbi.nlm.nih.gov/10903330/ https://pubmed.ncbi.nlm.nih.gov/24281010/ https://pubmed.ncbi.nlm.nih.gov/22385956/ Modern medicine only treats insulin resistance as a way to control blood sugar and ignore all the other organs which are affected due to their chronically inflamed and dysfunctional state.
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ostermayer 4 months ago
not sure the audiobook industry has much future. now i just have a llm powered voice system read me epubs.